IGNORANCE IS BLISS

Men's Health compiled this list based on antidepressant sales, courtesy of NDC Health; suicide rates, from the Centers for Disease Control and Prevention (CDC); and the number of days inhabitants reported being depressed, based on the CDC's Behavioral Risk Factor Surveillance System, accessed through bestplaces.net.

Where can you find happiness? Texas, that's where. Three of its cities placed in the top four: number one, Laredo; number two, El Paso; and number four, Corpus Christi.

The 20 Happiest Cities

1. Laredo, TX: A+

2. El Paso, TX: A+

3. Jersey City, NJ: A+

4. Corpus Christi, TX: A+

5. Baton Rouge, LA: A

6. Honolulu, HI: A-

7. Fresno, CA: A-

8. San Jose, CA: A-

9. Lincoln, NE: B+

10. Bakersfield, CA: B+

11. Buffalo, NY: B+

12. Anchorage, AK: B+

13. Stockton, CA: B+

14. Shreveport, LA: B+

15. (3-way tie) Madison, WI: B, Montgomery, AL: B, and Des Moines, IA: B

18. Wichita, KS: B

19. (tie) Sacramento, CA: B and Omaha, NE: B

The 20 Most Depressed Cities

1. Philadelphia, PA: F

2. Detroit, MI: F

3. St. Petersburg, FL: F

4. St. Louis, MO: F

5. Tampa, FL: F

6. Indianapolis, IN: F

7. (3-way tie) Mesa, AZ: F, Phoenix, AZ: F, and Scottsdale, AZ: F

10. Cleveland, OH: F

11. New York, NY: D-

12. Salt Lake City, UT: D-

13. Atlanta, GA: D

14. (3-way tie) Yonkers, NY: D, Pittsburgh, PA: D, and Kansas City, MO: D

17. (3-way tie) Long Beach, CA: D, Los Angeles, CA: D, Nashville, TN" D

20. Portland, OR: D